The MiaGB consortium is one of the largest efforts of several pioneer scientists in the microbiome and aging research to develop a deeper understanding of how the microbiome impacts our gut, brain, and muscle health. A team of multidisciplinary investigators is combining powerful multi-omics using cutting-edge technologies of metagenomics, metabolomics, transcriptomics, proteomics, genotyping, immunophenomics, mitochondrial function, and artificial intelligence to develop a unique resource and databank for the microbiome in aging researchers.
If you are interested to collaborate for ancillary studies, secondary analyses, and new sites, please contact us
Peer-Reviewed Manuscripts (Total : 10)
Zanini BM, de Avila BM, Garcia DN, Hense JD, Veiga GB, Barreto MM, Ashiqueali S, Mason JB, Yadav H, Masternak M, Schneider A. Dynamics of serum exosome microRNA profile altered by chemically induced estropause and rescued by estrogen therapy in female mice. GeroScience. 2024 Mar 19:1-9.
Carris NW, Mhaskar R, Coughlin E, Bracey E, Tipparaju SM, Reddy KR, Yadav H, Halade GV. Association of Common Foods with Inflammation and Mortality: Analysis from a Large Prospective Cohort Study. Journal of Medicinal Food. 2024 Feb 14.
Mishra SP, Jain S, Wang B, Wang S, Miller BC, Lee JY, Borlongan CV, Jiang L, Pollak J, Taraphder S, Layden BT. Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function. JCI insight. 2024 Feb 8;9(3).
Miller BC, Mathai M, Yadav H, Jain S. Geroprotective potential of microbiome modulators in the Caenorhabditis elegans model. GeroScience. 2024 Feb;46(1):129-51.
Ashiqueali SA, Chaudhari D, Zhu X, Noureddine S, Siddiqi S, Garcia DN, Gostynska A, Stawny M, Rubis B, Zanini BM, Mansoor MA. Fisetin modulates the gut microbiota alongside biomarkers of senescence and inflammation in a DSS-induced murine model of colitis. GeroScience. 2024 Jan 8:1-9.
Saliva protein markers to predict cognitive impairment in older adults. Molecular and Cellular Proteomics (under-preparation).
Sacchetti P, Jain S, Yadav H, Paoli A. Impact of ketogenic diet on metabolic and brain health. Frontiers in Neuroscience. 2023 Jan 9;16:1107741.
Dixon SA, Jain S, Mabundo L, Krenek A, Estrada DE, Yadav H, Chung ST. The effects of prebiotics on gastrointestinal side effects of metformin in youth: A pilot randomized control trial in youth-onset type 2 diabetes. Frontiers in Endocrinology. 2023 Feb 23;14:1125187.
Chaudhari DS, Jain S, Yata VK, Mishra SP, Kumar A, Fraser A, Kociolek J, Dangiolo M, Smith A, Golden A, Masternak MM. Unique trans-kingdom microbiome structural and functional signatures predict cognitive decline in older adults. GeroScience. 2023 Oct;45(5):2819-34.
Masternak MM, Yadav H. Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging. Aging pathobiology and therapeutics. 2022;4(1):1.
Abstracts (Total : 12)
Jayden A. Haggler, Brandi C. Miller, Rohit Shukla, Vivek Kumar, Diptaraj S. Chaudhari, MiaGB consortium, Hariom Yadav, and Shalini Jain. “Neurocognitive Implications of the Gut Microbiome in Older Cancer Survivors of the MiaGB Consortium.” At the 149th Annual Meeting of the American Neurological Association, Orlando, FL, USA on September 14-17, 2024.
Brandi C. Miller, Mihir S. Kulkarni, Rohit Shukla, Vivek Kumar, Diptaraj S. Chaudhari, MiaGB consortium, Hariom Yadav, and Shalini Jain. “Gut microbiota and its metabolites in cognitive impairment in older adults of the MiaGB Consortium.” At the 149th Annual Meeting of the American Neurological Association, Orlando, FL, USA on September 14-17, 2024.
Adewale S. James, Diptaraj S. Chaudhari, Shalini Jain, Dayna Goltz, Divyani Tangudu, Hariom Yadav, and MiaGB consortium, “Specific Microbiome Signature Dynamics Could Predict Aging Continuum and Cognitive Impairment in Older Adults“, At the American Physiological Society (APS) Summit 2024, Long Beach, California, USA on April 4th to 7th, 2024.
Brandi C. Miller, Jayden A. Haggler, Diptaraj S. Chaudhari, Hariom, Shalini Jain, and MiaGB consortium. “Cognitive function, diet, and gender are associated with unique microbiome signatures in cancer survivors” at the 2024 American Physiology Society Annual Summit in Long Beach, CA on April 4-7, 2024.
Adewale S. James, Diptaraj S. Chaudhari, Noorul A. Adil, Shalini Jain, Dayna Goltz, Divyani Tangudu, and Hariom Yadav, “Linking Gut Virome Signatures to Cognitive Health” in Aging at the USF 34th Annual USF Health Research Day 2024 at the University of South Florida, Tampa, Florida, on March 1, 2024.
Lauren Buddendorff, Sidharth P. Mishra, Shalini Jain, Hariom Yadav, The Triad of Leaky Gut, TLR4, and Inflammation: A Pathway to Mild Cognitive Impairment at the USF 34th Annual USF Health Research Day 2024 at the University of South Florida, Tampa, Florida, on March 1, 2024.
Adewale S. James, Diptaraj S. Chaudhari, Noorul A. Adil, Shalini Jain, Dayna Goltz, Divyani Tangudu, and Hariom Yadav, “Linking Gut Virome Signatures to Cognitive Health in Aging” at the USF Graduate Students Research Symposium, 2024 at the University of South Florida, Tampa, Florida, on March 22nd, 2024.
Sima Maleki, Jain Shalini, and Hariom Yadav, “From Hypertension to Anti-Aging: Exploring the Repurposing of Natural Compounds”, at the 34th Annual USF Health Research Day 2024 at the University of South Florida, Tampa, Florida, on March 1, 2024.
Jayden A. Haggler, Brandi C. Miller, Diptaraj S. Chaudhari, Rohit Shukla, Hariom Yadav, Shalini Jain, and MiaGB consortium, “Unique gut microbiome signatures in cancer survivors and implications for cognitive health”, at the 34th Annual USF Health Research Day 2024 at the University of South Florida, Tampa, FL, on March 1, 2024.
Jayden Haggler, Brandi Miller, Diptaraj Chaudhari, Hariom Yadav, and Shalini Jain, “Unique Microbiome Signatures Related to Cancer Survivorship and Cognitive Decline in Older Adults“, at the Gerontological Society of America (GSA) 2023 Annual Scientific Meeting in Tampa, Florida, on November 8-11, 2023.
Diptaraj Chaudhari, Shalini Jain, Corinne Labyak, Adam Golden, Mia GB, Peter Holland, Michal Masternak, and Hariom Yadav, “Unique Microbiome-Proteome Signatures of Saliva in Prediction of Cognitive Decline in Older Adults of MiaGB Cohort“, at the GSA 2023 Annual Scientific Meeting in Tampa, Florida, on November 8-11, 2023.
Sherri Huang, Diptaraj Chaudhari, Pushti Kanani, Wesley Burrow, Yi Lin, Robert Mankowski, Shalini Jain, and Hariom Yadav, “Large-Scale Analysis of Human Gut Microbiota Patterns Across Geography and Pediatric to Geriatric Ages“, at the GSA 2023 Annual Scientific Meeting in Tampa, Florida, on November 8-11, 2023.
Diptaraj Chaudhari, Shalini Jain, Hariom Yadav, Michal Masternak, Peter Holland, Marc Agronin, MiaGB Consortium Team, “Unique Transkingdom Microbiome Signatures Linked With Cognitive Decline In Older Adults Of MiaGB Consortium Cohort“. Innovation in Aging. 2022 Nov;6(Suppl 1):767.
Vinod Yata, Shalini Jain, Michal Masternak, Peter Holland, Marc Agronin, Hariom Yadav, MiaGB Consortium Team “Saliva Based Biomarkers To Identify Cognitive Impairment In Older Adults“. Innovation in Aging. 2022 Nov;6(Supplement_1):813-4.